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Starbucks Bottled Frappuccino: How Much Caffeine, Sugar, Calories The Starbucks Bottled Frappuccino contains 110 mg caffeine to give you the boost for the day. It has 47 g sugar which is low but may not be for some people like people with diabetes. The Starbucks Bottled Frappuccino has 300 calories which are much more than many other caffeinated drinks. References: Calories in Starbucks Vanilla Frappuccino (13.7 oz) and Nutrition Facts There are 290 calories in 1 bottle (13.7 oz) of Starbucks Vanilla Frappuccino (13.7 oz). Get full nutrition facts for other Starbucks products and all your other favorite brands. ... of Starbucks Vanilla Frappuccino (13.7 oz). Calorie breakdown: 15% fat, 72% carbs, 12% protein. Related Iced Coffee from Starbucks: Cold Brew Dark Chocolate ... Caramel Frappuccino® Blended Beverage - Starbucks® Calories 380 Calories from Fat 140 % Daily Value * Total Fat 16 g 21% Saturated Fat 10 g 50% Trans Fat 0 mg Cholesterol 50 mg 17% Sodium 230 mg 10% Total...